How Polynucleotides Work
What is a biostimulator?
Categorised as a ‘biostimulator’ rather than a conventional dermal filler, Polynucleotides work on the cells of the skin to revitalise and rejuvenate them, instead of filling lost volume.
When injected into the skin, the DNA fragments mimic human DNA and start collagen and elastin neogenesis. This process naturally thickens the epidermis and promotes fibroblast production – resulting in overall improvement of skin hydration.
The polynucleotide injections also provide antioxidant and anti-inflammatory benefits, effectively reducing skin inflammation and improving overall skin health.
What areas can polynucleotide treatment improve?
As polynucleotides work on the skin at a cellular level, they can be used anywhere around the body where the skin needs rejuvenation and regeneration.
Improvements have been noted when polynucleotides were used:
- under eye trough
- face
- neck
- decolletage
- hands
Due to its anti-inflammatory effects, you can also use this on scars, pigmented areas, acne and stretch marks.
What is the evidence that polynucleotides work?
There are studies which show polynucleotide injections have proven benefits, and are here to stay.
One such Italian study, in 2021, showed over 80% of participants reported an improvement on their face, periocular area, décolleté and neck, hands, scalp, and stretch marks.
The study concluded:
The expert consensus illustrates the value of intradermal PH HPT™ as biostimulatory boosters for priming and revitalisation of face and body skin, thanks to their efficacy on dermal cells.
